Neonatal Jaundice
Biliary atresia
Breast feeding jaundice
Breast milk jaundice
Hemolytic anemia
Kernicterus
Physiologic jaundice
- Describe liver anatomy and the physiology of bilirubin metabolism and excretion
- Describe the functions of the liver and interpret tests of liver function, hepatocellular function and cholestasis
- Differentiate between conjugated and unconjugated hyperbilirubinemia
- Describe blood group type and antigens, and explain the mechanism whereby blood group incompatibility can affect bilirubin metabolism
Overview & Foundational Knowledge
Bryon J. Hyperbilirubinemia in the Newborn. Pediatrics in Review 2011; 32(8): 341-349.
Some foundational knowledge on bilirubin metabolism. Discusses physiologic versus pathologic hyperbilirubinemia. More focus on unconjugated hyperbilirubinemia (e.g. breast milk and breastfeeding jaundice). |
Brumbaugh D & Mack C. Conjugated hyperbilirubinemia in children. Pediatrics in Review 2012; 33(7): 291-302.
Foundational knowledge. Addresses cholestasis in newborns and older children. Addresses the importance of early diagnosis in newborns. Good visuals. |
Clinical Resources
Guidelines for the detection, management and prevention of hyperbilirubinemia in term and late preterm newborn infants
http://www.cps.ca/documents/position/hyperbilirubinemia-newborn http://www.cps.ca/fr/documents/position/hyperbilirubinemie-nouveau-nes Canadian Paediatric Society Position Statement (2007, 2011) |
Cards
Neonatal Jaundice
Canuc-Paeds physician authored, replayable cases |